SMARD1 is an inherited condition that causes muscle weakness and respiratory failure typically beginning in infancy. We are on a mission for a CURE! smashSMARD was started to bring a permanent end to SMARD, CMT2S and IGHMBP2-related disorders. 100% of every donation is being used to develop a life-saving gene therapy for those affected. smashSMARD is a non-profit 501(c)3 organization which mission is to increase awareness of SMARD1 and the IGHMBP2 gene mutation in order to fund research that will lead to treatments and cures.