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Raising the bar through research Cri Du Chat Research Foundation Raising the bar through research. In 1963 Dr. Jerome Lejeune became the first person to research and describe the syndrome that eventually became known as Cri Du Chat 5pminus Syndrome. However the technology of that generation would only allow him and future researchers to scratch the surface of this rare genetic disorder that affects approximately 1 out of 15000 to 50000 live births a year.