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Clarke County Development Corporation Osceola Iowa Business Development Opportunities in South Central Iowa Clarke County Development Corporation For more than a half century the Clarke County Development Corporation has been dedicated to strengthening the economic development of southern Iowa through the growth of our business and industry the addition of new an innovative industry to our communities and the improvement of the quality of life enjoyed by our residents. MORE Southern Iowa Community Spotlight Located in the heart of southern Iowa Clarke County offers an ideal location at the junction of US Highway 34 and Interstate 35. The quality of our workforce is next to none. We offer a variety of business assistance programs that foster the economic development of the area.