Lynch Syndrome International
MISSION STATEMENTThe primary mission of Lynch Syndrome International (LSI) is to serve our global communities by focusing on providing support for individuals afflicted with Lynch syndrome, creating public awareness of the syndrome, educating members of the general public and health care professionals and providing support for Lynch syndrome research endeavors.LSI, an all volunteer organization, is founded and governed by Lynch syndrome survivors, their families, and health care professionals who specialize in Lynch syndrome.If diagnosed early, we believe Lynch syndrome survivors have favorable outcomes which enhance survival, the longevity and quality of life as well as the emotional well-being of the afflicted.With the provisions of knowledge, caring and respect for those living with Lynch syndrome, coupled with a common theme of a prevalent positive attitude, we can be change agents, enhancing hope and survivability, impacting the life of countless thousands of people throughout our world.
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Home - Lynch Syndrome International LYNCH SYNDROME Lynch Syndrome is a hereditary disorder caused by a mutation in a mismatch repair gene in which affected individuals have a higher than normal chance of developing colorectal cancer endometrial cancer and various other types of aggressive cancers often at a young age also called hereditary nonpolyposis colon cancer. HNPCC PROTECTING OUR FAMILIES AND OURSELVES Mutation The mutations of specific mismatch repair MMR genes including but not limited to MLH1 MSH2 MSH6 PMS2 and EPCAMTACSTD1 deletions are responsible for Lynch syndrome. These genes work in repairing mistakes made when DNA is copied in preparation for cell division. The defects in the genes disallow repair of DNA mistakes and as cells divide errors stack and uncontrollable cell growth may result in cancer.
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