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Welcome to the Kate Foundationfor Rett Syndrome Research The Kate Foundation for Rett Syndrome Research is a 501c3 nonprofit organization dedicated to raising funding for scientific research seeking the reversal of Rett Syndrome and the relief of Rett Syndrome symptoms. Funds raised by the Kate Foundation go to the Rett Syndrome Research Trust a501c3 nonprofit organization intensively focused on the development of treatments and cures for Rett Syndrome and related MECP2 disorders. Since 2009 the Kate Foundation has raised over 900000 for this research. Rett Syndrome is a neurological disorder caused by a mutation in a gene called MECP2.