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HOME HARTWELL BLOG ABOUT RESOURCES JOIN More Welcome to the neighborhood. HARTWELL OHIO Hartwell holds the distinction as Cincinnatis northernmost neighborhood and is situated in the Mill Creek Valley along Vine St Cincinnatis own Main Street. Annexed to the City of Cincinnati 100 years ago it is home today to approximately 4500 residents who enjoy its central location convenient access to I75 Ronald Reagan Highway the 78 Metro bus route to downtown and its walkable neighborhood business district that provides a broad array of local retail. Hartwellians take pride in the communitys treelined streets recreational opportunities health care facilities neighborhood school and affordable housing.