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Who We Are The Isabella Santos Foundation ISF is a 501c3 nonprofit dedicated to funding groundbreaking research clinical trials and survivorship programs that focus on underfunded and often overlooked cancers. Driven by Isabellas legacy of hope resilience and the power of building a sense of community ISF raises essential funds for to provide transformational outcomes for rare cancer heroes worldwide. Our passion lies within the belief that every child deserves to receive the care they need to survive and thrive. Since 2007 ISF has been a beacon of hope leading collaborative efforts with medical institutions.