The Medical Letter, Inc.

A nonprofit organization that has been providing independent reviews of drugs and therapeutics since 1959. Funded solely by subscriptions and donations. The Medical Letter is committed to providing objective, practical, and timely information on drugs. The Medical Letter's mission is to provide objective, practical, and timely information on drugs and treatments of common diseases so that our readers can make the best decisions for their patients—without the influence of the pharmaceutical industry. Our publication is intended specifically to meet the needs of busy healthcare professionals who want unbiased drug information. The Medical Letter is funded by subscription fees. We do not receive commercial support. We do not sell advertising or reprints of our articles to pharmaceutical companies.Many of our readers are aware that manufacturers and their representatives may exaggerate the therapeutic effects and understate the adverse effects of their products, but have neither the time nor the resources to check the accuracy of the manufacturers' claims. Our editorial process is designed to ensure that our drug information represents an unbiased consensus of scientific experts.If a new prescription drug offers genuine advantages over older drugs, we say so.If a new prescription drug offers no advantage, if its effectiveness is limited, or if it is too toxic or too expensive to justify its use, we say so. If new drug information changes the status of previously reviewed drugs, we publish follow-up reports.
131881832
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1959
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- B11 -

Home The FDA has approved suzetrigine Journavx Vertex a selective sodium channel blocker for oral treatment of moderate to severe acute pain in adults. Suzetrigine is the first sodium channel blocker to be approved in the US for this indication and the first oral nonopioid drug to be approved for treatment of pain in over 25 years. STANDARD TREATMENT Nonopioid drugs are preferred for treatment of pain. In patients with moderate to severe acute pain use of an NSAID plus acetaminophen may be at least as effective as an oral opioid combined with acetaminophen or even an injected opioid.

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