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Friends of Missiquoi National Wildlife Refuge Visiting the Refuge Trails are open every day from dawn until dusk and the Refuge Visitor Center is open daily Monday through Friday. Visitors are welcome to view the many educational exhibits learn about refuge management programs and find out whats going on at the refuge to benefit both wildlife and people. The Refuge Visitor Center hours are Refuge Trails The Missisquoi Refuge offers some excellent trails for walking snowshoeing and crosscounty skiing. Click map for a larger view.