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Home What is Lynch Syndrome Education Advocacy Resources Donate Headlines About More Check out the Lynch syndrome awareness day social media toolkits AliveandKick39n LIVING WITH LYNCH SYNDROME what is lynch syndrome. Lynch syndrome is a genetic condition that increases a person39s risk for certain cancers. It is the most common inherited cause of colorectal and endometrial cancers. People with Lynch syndrome have a defect in a gene that helps repair damaged DNA which can lead to the development of cancerous cells.