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OHF Oxalosis Hyperoxaluria Foundation Our Vision Working together to end Hyperoxaluria OHF is leading the way to a cure advancing care and research and transforming the lives of those affected by Hyperoxaluria Learn More about the OHF Understanding Hyperoxaluria Hyper too much oxal oxalate uria in the urine Hyperoxaluria can be caused by a genetic disorder eating too many oxalaterich foods or an intestinal disease. In some people the cause of the disease is not known but may result from changes in the way kidneys handle normal amounts of oxalate. Early diagnosis and treatment are important to the longterm health of your kidneys. Learn More About Understanding Hyperoxaluria Living with Hyperoxaluria Being diagnosed with hyperoxaluria can be overwhelming.