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Working Together to Optimize Neurodevelopment and Quality of Life Cardiac neurodevelopment includes all aspects of motor language cognitive socialemotional and psychological development throughout life for individuals with pediatric and congenital heart disease. Children with heart disease can have challenges in one or more of these areas. While some of these challenges are picked up during infancy or early childhood others may not develop until later childhood adolescence or even adulthood. CNOC is a collaborative of clinicians researchers patients and families from across the world working together to address these challenges and improve neurodevelopment mental health and quality of life for people of all ages and stages with pediatric and congenital heart disease.