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Mission Contact More Dear Friends and Supporters I am writing to you with a heart full of gratitude and appreciation. When we founded The Calliope Joy Foundation in 2013 our mission was to drive awareness fund research and support families affected by leukodystrophy. Thanks to your unwavering generosity and advocacy we have seen what once seemed impossible become a reality. With this years FDA approval of gene therapy treatment for Cals disease metachromatic leukodystrophy MLD.