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The chamber of momentum The chamber of having fun The chamber of leadership The Greater San Antonio Chamber of Commerce With more than 1750 members the Greater San Antonio Chamber of Commerce is the largest and most influential probusiness organization in the region. As the primary voice of business in our city the Chamber mobilizes members to promote and drive important initiatives that benefit San Antonio. For over 130 years our success has centered on our ability to bring together members and leaders from all areas of our city to address the regions issues and unique challenges. We also serve as a resource to connect our members to business growth through our events sponsorships and networking opportunities.