Giving hope to millions of youth around the globe. Our mission gives hope and opportunity to millions of youth around the globe. What's your mission? Salesian Missions, headquartered in New Rochelle, New York, is part of the Don Bosco Network — a worldwide federation of Salesian non-governmental organizations. The mission of the U.S.-based nonprofit Catholic organization is to provide support and raise funds to assist needy youth and families through programs carried out by Salesian missionaries. Millions of youth facing adversity have received services specifically funded by Salesian Missions and its donors. Funds are also raised to assist with humanitarian emergencies caused by natural disasters, wars and violence.