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MPN Education Foundation Conferences Donate Help us help inform others. Join the MPNNET Online Support The mission of MPNNET and Online Forum is to bring information education and support to our members 2021 MPN Heroes Recognition Program Nominations will open soon for the 2021 MPN Heroes Recognition Program. Myeloproliferative Neoplasms Myeloproliferative neoplasms MPN are relatively rare chronic hematologic malignancies that include the classic Myeloproliferative Neoplasm Disorders Philadelphia chromosomenegativeEssential Thrombocythemia ETMyelofibrosis MFPolycythemia Vera PV Philadelphia chromosomepositiveChronic Myelogenous Leukemia CML There are atypical Myeloproliferative Neoplasm Disorders which include molecularly defined PDGFRArearranged eosinophilicmast cell disorders PDGFRBrearranged eosinophilic disorders systemic mastocytosis associated with ckit mutation 8p11 Myeloproliferative syndrome and juvenile myelomonocytic leukemia with recurrent mutations of RAS. MPN also includes the clinicopathologically assigned variants chronic neutrophilic leukemia chronic eosinophilic leukemia hypereosinophillic syndrome chronic basophilic leukemia chronic monomyelomonocytic leukemia systemic mastocytosis and unclassified myeloproliferative disorder.