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Main navigation Our aim is to promote safe compassionate ethical and evidenceinformed healthcare for children adolescents and young adults with gender dysphoria Latest from SEGM SEGM in Media Dispute arises over World Professional Association for Transgender Healths involvement in WHOs trans health guideline Letters to WHO from the Society for Evidence Based Gender Medicine SEGM which has itself commissioned several forthcoming relevant systematic reviews and the Clinical Advisory Network on Sex and Gender CANSG a network of mainly UK and Irish clinicians raised the question of whether WHO would be evaluating the benefits and harms of hormonal treatments for gender incongruenceor if instead it has taken a policy position on this without critically appraising the evidence as a letter from CANSG put it. 20241030 Gender medicine in the US how the Cass review failed to land The review by Hilary Cass paediatrician and former president of the Royal College of Paediatrics and Child Health was commissioned by the NHS and built on the findings of Casss 2022 interim report. Then she found that the evidence underpinning the treatment intensive gender affirming model of care for distressed young people was limited and inconclusive. The final report is even clearer The reality is that we have no good evidence on the long term outcomes of interventions to manage gender related distress.