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Melrose Chamber of Commerce Welcome to the Melrose Chamber of Commerce. The Melrose Chamber of Commerce is an independent private 501c6 organization with over 300 members helping businesses in and around the City of Melrose Massachusetts grow and succeed through networking advocacy communications events and more. The Chamber is the largest organization in Melrose dedicated to increasing economic activity through an involved membership representing a variety of industries and business sectors. Events The Melrose Chamber of Commerce hosts dozens of member networking events and also produces several community events throughout the year that promote our members and allow the community to come together for fun entertainment shopping and more.