Mission: Improve the health and lives of people affected by poverty or emergencies without regard to politics, religion, or ability to pay. Direct Relief is a medical relief organization, active in all 50 states and more than 80 countries, with a mission to improve the health and lives of people affected by poverty or emergency situations. Direct Relief earns a 100% fundraising efficiency rating from Forbes, tops Charity Navigator's list of the "10 Best Charities Everyone's Heard Of" and is named among "the world's most innovative companies in not-for-profit" by Fast Company.