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Arthrogryposis Multiplex Congenita Promoting Awareness Among Providers and Families Arthrogryposis Multiplex Congenita Arthrogryposis Multiplex Congenita AMC is a condition affecting 1 in 3000 babies. It is characterized by contractures stiffness in two or more joints resulting in decreased range of motion and muscle function. There are various types and causes of AMC. Joint contractures can often be detected by ultrasound during pregnancy but more than half of all cases go undetected until after birth.