
Home | Gladstone Institutes
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San Francisco, CA 94158 United States
gladstoneinstitutes.org
GladstoneInst
gladstoneinstitutes
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News

Bioinformatics Fellow Sarah Nyquist explains her research on lactation. Learn more about Nyquist's work: https://bit.ly/3H0pqff (fb)

Imagine looking at thousands of scattered puzzle pieces and trying to guess what picture they create. Without any reference point, it’s nearly impossible. In a similar way, biologists today face major challenges when trying to make sense of enormous datasets generated by experiments that profile thousands of individual cells. With so much genomic information at hand—but without much context—it can be difficult to understand how that data translates to human health and disease. Researchers address this by defining cell types, akin to deciding how to sort puzzle pieces by color or pattern before assembling them. But just as it is hard to collaborate on a puzzle if your partner uses different criteria to sort pieces, scientists have been stymied by how to compare cell types across studies. Now, a team at Gladstone Institutes has unveiled a powerful computational tool that solves this problem. The new method, called CellWalker2, allows scientists to determine how cell types are related and identify cell groupings that may impact health, leading to a better understanding of the cells they’re studying. Read more about this study: https://bit.ly/3FjfcGk (fb)

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About the organization
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Gladstone NOW The Campaign Join Us on the Journey Apply to the PUMAS Internship Program Watch the Video Never Before Now NOMISGladstone Fellowships for Exceptional Postdoctoral Scientists Our Gladstone pushes the boundaries of scientific possibility through our five interconnected institutes. With a deep understanding of how the human body works and what goes wrong in disease we focus on conditions with profound medical economic and social impact. Our Institutes Cardiovascular Disease Congenital Heart Disease Heart Failure Genetic Diseases Regenerative Medicine Data Science and Biotechnology Artificial Intelligence Computational Biology CRISPR Genome Editing Genetic Diseases Proteomics Synthetic Biology Genomic Immunology Cancer Autoimmune Diseases Infectious Diseases Primary Immunodeficiencies Neurological Disease Alzheimers Disease Other Dementias ALS Autism Epilepsy Huntingtons Disease Long COVID Multiple Sclerosis Parkinsons Disease Rare Brain Diseases Spinal Cord Injury Traumatic Brain Injury Virology HIVAIDS AntimicrobialResistant Infections COVID19 and Long COVID Womens Health Influenza Microbiome and Gut Health Phage Therapy Respiratory Viruses Hepatitis C Vaccine Development Zika Malaria Latest News Our scientists pursue research with extraordinary levels of creativity and courage. We recognize the momentous era in which we live and ask questions relentlessly knowing the next key discovery may occur in an instant.
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