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Together We Can Help us rewrite the future for children afflicted with de novo spastic paraplegia a swift and severe neurodegenerative disease. About Us Learn more about our work our team and some of the resilient children battlingthis devastating disease. About SPG4 Find out more about spastic paraplegia SPG4 and how a SPAST mutation impacts the body. Research Read more about the promising projects and research for a treatment or cure.