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Making Breakthroughs Possible The most prevalent diseases youve never heard of What are MECFS Long Covid. Myalgic encephalomyelitis ME formerly known as chronic fatigue syndrome CFS is a chronic complex neuroimmune disease that profoundly limits the health and productivity of patients and is often triggered by an infection. Long Covid describes a collection of lingering symptoms following COVID19. They are thought to be related as they both can follow infection and exhibit many of the same prevalent symptoms crippling fatigue postexertional malaise and cognitive dysfunction.