Tay-Sachs Awareness and Prevention Organization Tay-Sachs Awareness and Prevention Organization's primary mission is to prevent Tay-Sachs in the general population of the U.S. TSAPO uses genealogical research to identify individuals who have a higher risk of being a Tay-Sachs carrier so they can be tested and know their status. We also help families who have been affected by Tay-Sachs have healthy children through grants for assisted reproductive technology and adoption. Tay-Sachs is a fatal genetic condition that can affect anyone regardless of ancestral background, and with a carrier rate of 1 in 250 people in the United States, everyone should get tested to know their carry status.