WiCell Research Institute

WiCell Research Institute is a nonprofit organization dedicated to advancing stem cell technologies. Established in 1999, it serves as a supporting organization of the University of Wisconsin–Madison, contributing significantly to the field of human pluripotent stem cell research.

Mission and Activities

WiCell's mission is to provide high-quality stem cell lines and characterization services, aiming to advance regenerative medicine and cell and gene therapy globally. The organization offers a diverse range of human pluripotent stem cell lines, including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), disease models, genetically modified variants, and cGMP grade cell lines. Its services include cell banking, characterization testing, and distribution of stem cell lines, as well as quality control testing and long-term liquid nitrogen storage solutions[1][3].

History and Achievements

In its early years, WiCell played a pivotal role in hosting the National Stem Cell Bank, which collected, banked, characterized, and distributed the 21 human embryonic stem cell lines approved for federal funding in the U.S.[1]. The institute has also provided training to over 800 scientists worldwide and has licensed human embryonic stem cell lines to more than 500 researchers across 32 countries and 42 states[2].

Services and Impact

WiCell's Stem Cell Bank is renowned for its comprehensive collection of cell lines submitted by researchers globally. The bank supports both academic and commercial research, offering characterization services such as karyotyping, fluorescence in situ hybridization (FISH), microarray analysis, and mycoplasma testing[1][3]. WiCell collaborates with other entities to facilitate the distribution of extensively characterized cell lines, enhancing the availability of NIH-eligible lines for U.S. researchers[2].

Partnership and Recognition

WiCell has collaborated with entities like Cellartis AB to deposit cell lines with the U.S. National Stem Cell Bank, furthering the accessibility of highly characterized human embryonic stem cell lines[2]. The institute is recognized for its commitment to quality and innovation, supporting groundbreaking research and clinical applications[3].